Immunology of age-related macular degeneration
نویسندگان
چکیده
منابع مشابه
the genetics of age-related macular degeneration
age-related macular degeneration (amd) is the leading cause of blindness in old subjects. it is a multifactorial disease with both environmental and genetic factors playing some role in its pathogenesis. similar to many other genetic diseases, the inheritance pattern of amd does not fit into simple mendelian rules. these diseases are caused by the presence of multiple genetic factors and are ca...
متن کاملبررسی اثر چندشکلی ژنتیکی xrcc7 با ریسک ابتلا به بیماریamd age-related macular degeneration))
amd بیماری تحلیل شبکیه است که عامل اصلی کوری در افراد بالای 55 سال در جهان غرب به شمار می-رود. در اثر این بیماری، لیپوپروتئین ها در شبکیه تجمع پیدا کرده و رگ زایی القاء می شود. ثابت شده است که عوامل ژنوتوکسیک محیطی مثل سیگار کشیدن، رژیم غذایی و نور در افراد پیر با زمینه ی ژنتیکی مستعد در بروز بیماری دخیل می باشند. بنابراین ما یک مطالعه ی مـورد- شاهـدی را ترتیب دادیم که شـامل 112 فرد مبتلا به am...
Measurement of Choroidal Neovascular Area in Age-Related Macular Degeneration using Modified Otsu’s Thresholding Method
Introduction: Age-related Macular Degeneration (AMD) is one of the most important causes of irreversible blindness in the developed world and prevents the affected person from performing simple tasks such as reading, driving and facial recognition. In the AMD, new blood vessels grow underneath the retina in a process called choroidal neovascularisation (CNV). There ...
متن کاملage-related macular degeneration: a scientometric analysis
age-related macular degeneration (armd) is a major cause of central blindness among working aged adults across the world. systematic research planning on any subject, including armd is in need of solid data regarding previous efforts in this field and to identify the gaps in the research. this study aimed to elucidate the most important trends, directions, and gap in this subject. the data extr...
متن کاملAssociation of CFI gene polymorphism with age related macular degeneration in Northwest of Iran
Background & Aims: To investigate the association of CFI p.Gly119Arg polymorphism with Age-related macular degeneration (AMD). Materials & Methods: In this case-control study, the association of p.Gly119Arg polymorphism in CFI gene was investigated in 65 patients suffering from AMD and150 healthy age, sex and ethnicity matched unrelated people as control group. Both of the case and cont...
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ژورنال
عنوان ژورنال: Nature Reviews Immunology
سال: 2013
ISSN: 1474-1733,1474-1741
DOI: 10.1038/nri3459